Lipid-Based Nanoparticles in Cancer Diagnosis and Therapy

Figure 2

Schematic diagrams showing self-assembly of passively targeted Gd-ABC (top) and folate-receptor targeted Gd-ABCD nanoparticles (bottom) for IGROV-1 tumour imaging from combinations of structural lipids, PEG-lipids and imaging lipids [58, 59]. LTC: long-term circulation enabled by virtue of the use of bilayer stabilizing lipids and 7 mol% PEG-lipid in the outer leaflet membranes of nanoparticle structures.