Research Article

Targeted Antiepidermal Growth Factor Receptor (Cetuximab) Immunoliposomes Enhance Cellular Uptake In Vitro and Exhibit Increased Accumulation in an Intracranial Model of Glioblastoma Multiforme

Figure 6

Representative sections containing the U87 mg xenograft tumor showing accumulation of green fluorescent α-hEGFR-IL’s (A). In comparison, hIgG-IL’s accumulate to a lower degree within the tumor (B), but the fluorescence is clearly higher than that of background fluorescence obtained from U87 mg xenograft tumor not injected with liposomes (C). Arrows illustrate accumulation of liposomes within the tumor. Scale bar = 50 μm.
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