Targeted Antiepidermal Growth Factor Receptor (Cetuximab) Immunoliposomes Enhance Cellular Uptake In Vitro and Exhibit Increased Accumulation in an Intracranial Model of Glioblastoma Multiforme

Table 1

Characterization of liposomes with respect to particle size, polydispersity, charge, and protein coupling yield.

	Particle size (nm)	Polydispersity	Zeta potential mV	µg protein/µmol PL
𝛼−hEGFR-IL	95.2±3	0.181±0.045	−1.99±0.067	97.6
hIgG-IL	119±12	0.199±0.091	−0.042±0.042	135.1
Naked liposomes	84.24±5	0.079±0.064	−0.06±0.023	N/A

EGFR-IL: liposomes coated with antiepidermal growth factor receptor (EGFR) antibody; hIgG-IL: liposomes coated with non-immune IgG; naked liposomes: liposomes without antibody conjugated to the surface; PL: phospholipids.