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Journal of Drug Delivery
Volume 2013 (2013), Article ID 513950, 11 pages
http://dx.doi.org/10.1155/2013/513950
Research Article

Simulation of Drug Release from PLGA Particles In Vivo

1Laboratory of Gastrointestinal Tract Reconstruction, Tohoku University, Graduate School of Biomedical Engineering, Japan
2Division of Surgical and Molecular Pathophysiology, Tohoku University, Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan
3Department of Colorectal Surgery, Tohoku University Hospital, 1-1 Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan

Received 3 June 2013; Revised 3 September 2013; Accepted 9 September 2013

Academic Editor: Viness Pillay

Copyright © 2013 Kaori Sasaki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. S. Shive and J. M. Anderson, “Biodegradation and biocompatibility of PLA and PLGA microspheres,” Advanced Drug Delivery Reviews, vol. 28, no. 1, pp. 5–24, 1997. View at Publisher · View at Google Scholar · View at Scopus
  2. R. A. Jain, “The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices,” Biomaterials, vol. 21, no. 23, pp. 2475–2490, 2000. View at Scopus
  3. J. Panyam, S. K. Sahoo, S. Prabha, T. Bargar, and V. Labhasetwar, “Fluorescence and electron microscopy probes for cellular and tissue uptake of poly(D,L-lactide-co-glycolide) nanoparticles,” International Journal of Pharmaceutics, vol. 262, no. 1-2, pp. 1–11, 2003. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Gaumet, R. Gurny, and F. Delie, “Fluorescent biodegradable PLGA particles with narrow size distributions: preparation by means of selective centrifugation,” International Journal of Pharmaceutics, vol. 342, no. 1-2, pp. 222–230, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. W. Liu, H. S. Choi, J. P. Zimmer, E. Tanaka, J. V. Frangioni, and M. Bawendi, “Compact cysteine-coated CdSe(ZnCdS) quantum dots for in vivo applications,” Journal of the American Chemical Society, vol. 129, no. 47, pp. 14530–14531, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. G. A. Challen and M. H. Little, “A side order of stem cells: the SP phenotype,” Stem Cells, vol. 24, no. 1, pp. 3–12, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. N. Haraguchi, H. Inoue, F. Tanaka et al., “Cancer stem cells in human gastrointestinal cancers,” Human Cell, vol. 19, no. 1, pp. 24–29, 2006. View at Scopus
  8. A. Quaroni, J. Wands, R. L. Trelstad, and K. J. Isselbacher, “Epithelioid cell cultures from rat small intestine. Characterization of morphologic and immunologic criteria,” Journal of Cell Biology, vol. 80, no. 2, pp. 248–265, 1979. View at Scopus
  9. C. Sundstrom and K. Nilsson, “Establishment and characterization of a human histiocytic lymphoma cell line (U-937),” International Journal of Cancer, vol. 17, no. 5, pp. 565–577, 1976. View at Scopus
  10. C. W. Scharenberg, M. A. Harkey, and B. Torok-Storb, “The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors,” Blood, vol. 99, no. 2, pp. 507–512, 2002. View at Publisher · View at Google Scholar · View at Scopus
  11. M. J. Tsung and D. J. Burgess, “Preparation and characterization of gelatin surface modified PLGA microspheres,” AAPS PharmSci, vol. 3, no. 2, p. E11, 2001. View at Publisher · View at Google Scholar · View at Scopus