Table 9: Effect of drug loading on CS : TPP weight ratio of 6 : 1.

DRZ loading (%)PS (nm)PIZeta potential (mV)EE of CSNs

Blank CSNs
25%
50%
75%

Values are expressed as mean ± standard deviation, .
CS: chitosan; TPP: tripolyphosphate; PS: particle size; NPs: nanoparticles; PI: polydispersity index; EE: entrapment efficiency; CSNs: chitosan nanoparticles; DRZ: dorzolamide hydrochloride.