Critical Assessment of Implantable Drug Delivery Devices in Glaucoma Management

Table 2

Examples of sustained release delivery systems for glaucoma that are under clinical development.

Drug	Implant type	Administration route	Manufacturer	Status	Information source
Bimatoprost	Sustained release punctal plug	Inserted into lid puncta	Vistakon Pharmaceuticals	Completed	[36, 37]
Latanoprost	Punctal plug	Inserted into lid puncta	QLT	Completed	[38]
Latanoprost	Biodegradable DURASERT (Latanoprost)	Subconjunctival implantation	pSivida Corp.	Ongoing	[39]
Latanoprost	Nonbiodegradable pellets of Latanoprost coated with EVA	Subconjunctival implantation	Aerie Pharmaceuticals	Ongoing	[40]
Travoprost	Sustained release travoprost punctum plug	Inserted into canaliculus of the eyelid	Ocular Therapeutix	Recruiting	[41]
Ciliary neurotrophic factor	Nonbiodegradable NT 501	Pars plana implantation	Neurotech	Ongoing	[42]
Latanoprost	Biodegradable slow release (SR) insert	Subconjunctival implantation	Sunil Deokule & Pfizer	Recruiting	[43]