Gene Therapy for Advanced Melanoma: Selective Targeting and Therapeutic Nucleic Acids

Table 1

Common melanoma-targeting tools: ligands for surface cellular targeting and promoters for tissue-specific transcription.

	Targeting tool	Target	Reference
Ligand	[Nle^4, DPhe^7]-α-MSH	MC1-R	[74–85]
	cRGD	𝛼v𝛽3	[86–90]
	LDV	𝛼1𝛽4	[91]
	Transferrin	Transferrin receptor	[92]
Promoter	Tyrosinase	—	[93–95]
	MIA	—	[96, 97]