The Signature Sequence Region of the Human Drug Transporter Organic Anion Transporting Polypeptide 1B1 Is Important for Protein Surface Expression

Figure 1

Regions of the OATP1B1 protein predicted to be α-helical by PHYRE2 [40], and the average positions of the TMs as predicted by the algorithms that gave a 12-TM model . The signature sequence is highlighted in yellow.