The Signature Sequence Region of the Human Drug Transporter Organic Anion Transporting Polypeptide 1B1 Is Important for Protein Surface Expression

<div>Predicted 12-TM topology of OATP1B1 with intracellular N and C termini. The FLAG epitope was inserted into the extracellular loop 2 between TMs 3 and 4 as directed by the topology predictions. The signature sequence is highlighted at the border between extracellular loop 3 and TM 6.</div>

Journal of Drug Delivery

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Figure 3

Figure 3: The Signature Sequence Region of the Human Drug Transporter Organic Anion Transporting Polypeptide 1B1 Is Important for Protein Surface Expression 

Figure 3 | The Signature Sequence Region of the Human Drug Transporter Organic Anion Transporting Polypeptide 1B1 Is Important for Protein Surface Expression 