The Signature Sequence Region of the Human Drug Transporter Organic Anion Transporting Polypeptide 1B1 Is Important for Protein Surface Expression

<div>Immunofluorescence of OATP1B1 negative control, OATP1B1-FLAG positive control, D251E, W254F, W258/259F, and N261A transiently transfected HEK293T cells, visualized by confocal microscopy. DAPI (blue) localized to the nucleus (504 nm) and FITC (green) localized to the FLAG epitope (488 nm). Scale bar = 20 <i>μ</i>M.</div>

Journal of Drug Delivery

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Figure 8

Figure 8: The Signature Sequence Region of the Human Drug Transporter Organic Anion Transporting Polypeptide 1B1 Is Important for Protein Surface Expression 

Figure 8 | The Signature Sequence Region of the Human Drug Transporter Organic Anion Transporting Polypeptide 1B1 Is Important for Protein Surface Expression 