Research Article
Mucoadhesive Hydrogel Films of Econazole Nitrate: Formulation and Optimization Using Factorial Design
| | Batch number | Econazole nitrate (mg per MHF) | PVA (% w/v of film forming gel) | Number of freeze/thaw cycles | PEG400 (% v/v of film forming gel) | Ethanol (% v/v of film forming gel) |
| | EF1 | 80 | 10 | 4 | 5 | 3 | | EF2 | 80 | 10 | 6 | 5 | 3 | | EF3 | 80 | 10 | 8 | 5 | 3 | | EF4 | 80 | 15 | 4 | 5 | 3 | | EF5 | 80 | 15 | 6 | 5 | 3 | | EF6 | 80 | 15 | 8 | 5 | 3 | | EF7 | 80 | 20 | 4 | 5 | 3 | | EF8 | 80 | 20 | 6 | 5 | 3 | | EF9 | 80 | 20 | 8 | 5 | 3 |
|
|
