Tailor-Made Pentablock Copolymer Based Formulation for Sustained Ocular Delivery of Protein Therapeutics

Table 1

Characterization of polymers.

Code	Structure	Total Mn^a; (theoretical)	Total Mn^b; (calculated)	Total Mn^c; (calculated)	Mw^c; (GPC)	PDI^c
PB-A	PGA300-PCL7500-PEG1000-PCL7500-PGA300	16600	15705	13781	18643	1.35
PB-B	PLA3450-PCL5700-PEG4000-PCL5700-PLA3450	22300	21034	19156	26978	1.41
PB-C	PEG550-PCL825-PLA550-PCL825-PEG550	3300	2910	4227	6044	1.43

a: theoretical weight of polymer.
b: molecular weight based on H-NMR.
c: molecular weight and PDI based on GPC.