Preparation and Characterization of Liquisolid Compacts for Improved Dissolution of Telmisartan

Table 1

Formulation details of telmisartan liquisolid tablets.

Formulation*	Vehicle		Avicel PH 102 (mg)	Aerosil 200 (mg)	Weight of tablet (mg)^#
F1	Transcutol HP	0.247	340	17	417
F2	Propylene glycol	0.224	375	18.75	453.75
F3	Polyethylene glycol 200	0.107	400	20	480
F4	Polyethylene glycol 600	0.101	500	25	585
F5	Tween 20	0.158	695	35	790
F6	Tween 80	0.139	610	30	700

Fixed powder excipient ratio () equal to 20 was used.
⁺Liquid load factor is defined as .
^#Final tablet weight includes 40 mg of disintegrant and 1% of lubricant.