Research Article
Design and Evaluation of Polyox and Pluronic Controlled Gastroretentive Delivery of Troxipide
Table 3
Physical characteristics of GRFTs (F1–F9).
| | Batch code | Tablet weight (mg) | Hardness (kg/cm2) | Drug content (%) | Tablet friability (%) | Floating lag time (s) | Total floating duration (h) |
| | F1 | 369.32 ± 2.70 | 5.5 ± 0.32 | 98.36 | 0.456 ± 0.03 | 39 | >12 | | F2 | 372.60 ± 1.50 | 6.4 ± 0.51 | 99.56 | 0.543 ± 0.01 | 52 | >12 | | F3 | 368.06 ± 2.33 | 6.8 ± 0.65 | 101.60 | 0.445 ± 0.04 | 64 | >12 | | F4 | 368.68 ± 2.15 | 6.2 ± 0.31 | 98.60 | 0.413 ± 0.02 | 59 | >12 | | F5 | 369.85 ± 1.75 | 7.1 ± 0.58 | 100.01 | 0.555 ± 0.01 | 60 | >12 | | F6 | 371.20 ± 2.94 | 7 ± 0.73 | 99.50 | 0.658 ± 0.02 | 74 | >12 | | F7 | 370.99 ± 1.75 | 5.5 ± 0.68 | 97.62 | 0.520 ± 0.03 | 61 | >12 | | F8 | 372.33 ± 2.56 | 5.9 ± 0.55 | 102.08 | 0.644 ± 0.01 | 56 | >12 | | F9 | 368.20 ± 2.11 | 5.6 ± 0.51 | 97.20 | 0.689 ± 0.04 | 76 | >12 |
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