Design and Evaluation of Polyox and Pluronic Controlled Gastroretentive Delivery of Troxipide

Table 4

Mathematical modeling and release kinetics for formulations F1–F9.

Batch code	Zero order	First order	Matrix	Hixson-Crowell	Korsmeyer-Peppas		Best fit model
	(^2)	(^2)	(^2)	(^2)	(^2)	()
F1	0.9941	0.8793	0.9618	0.9587	0.9995	0.8301	Korsmeyer-Peppas
F2	0.9748	0.9328	0.9678	0.9916	0.9870	0.8733	Korsmeyer-Peppas
F3	0.9801	0.9382	0.9478	0.9654	0.9789	0.6896	Zero order
F4	0.9937	0.9787	0.9396	0.9913	0.9953	0.9863	Korsmeyer-Peppas
F5	0.9912	0.8840	0.9574	0.9626	0.9937	0.8729	Korsmeyer-Peppas
F6	0.9950	0.9640	0.9426	0.9855	0.9959	0.8997	Korsmeyer-Peppas
F7	0.9711	0.9946	0.9696	0.9967	0.9841	0.7596	Hixson-Crowell
F8	0.9908	0.9657	0.9397	0.9849	0.9644	0.8007	Zero order
F9	0.9541	0.9839	0.9796	0.9778	0.9885	0.6185	Korsmeyer-Peppas

: diffusional exponent.