Hydroxypropyl-β-cyclodextrin: A Novel Transungual Permeation Enhancer for Development of Topical Drug Delivery System for Onychomycosis

Table 5

Evaluation of developed nail lacquer drug delivery formulations of terbinafine hydrochloride.

S. number	Formulation code	Drug content; (%); (mean ± S.D.) ()	Thickness; (mm); (mean ± S.D.) ()	Drying time; (sec); (mean ± S.D.); ()	Film glossiness*	Nonvolatile content; (mg); (mean ± S.D.); ()
1	L0	100.13 ± 2.2	0.2 ± 0.03	60 ± 5	++++	150 ± 3.0
2	L6	98.89 ± 3.1	0.2 ± 0.03	70 ± 5	++++	160 ± 2.1
3	L7	100.93 ± 5.0	0.2 ± 0.03	65 ± 5	+++	166 ± 3.2
4	L8	101.10 ± 3.3	0.2 ± 0.02	70 ± 5	++++	162 ± 2.3
5	L9	99.87 ± 3.5	0.2 ± 0.02	65 ± 5	+++	165 ± 4.2
6	L10	100.89 ± 2.5	0.2 ± 0.03	70 ± 5	+++	170 ± 3.2

++: good; +++: very good; ++++: excellent.