Formulation and In Vitro Evaluation of Bilayer Tablets of Nebivolol Hydrochloride and Nateglinide for the Treatment of Diabetes and Hypertension

Table 11

Flow properties of Nateglinide sustained release layer.

Batch code	Angle of repose	Bulk density (gm/cm^3)	Tapped density (gm/cm^3)	Carr’s index (%)	Hausner’s ratio
N1	35.12	0.32	0.37	13.50	1.15
N2	32.15	0.31	0.40	22.50	1.29
N3	31.18	0.34	0.38	10.52	1.11
N4	32.20	0.38	0.44	13.63	1.15
N5	34.80	0.30	0.35	14.28	1.16
N6	33.15	0.36	0.42	14.28	1.16
N7	30.00	0.29	0.33	12.12	1.13
N8	28.55	0.30	0.35	14.28	1.16
N9	27.50	0.31	0.35	11.42	1.13
N10	31.85	0.39	0.46	15.21	1.18
N11	27.90	0.34	0.40	15.00	1.17
N12	34.55	0.39	0.45	13.33	1.15
N13	34.41	0.33	0.38	13.15	1.15