Research Article
Formulation and In Vitro Evaluation of Bilayer Tablets of Nebivolol Hydrochloride and Nateglinide for the Treatment of Diabetes and Hypertension
Table 11
Flow properties of Nateglinide sustained release layer.
| Batch code | Angle of repose | Bulk density (gm/cm3) | Tapped density (gm/cm3) | Carr’s index (%) | Hausner’s ratio |
| N1 | 35.12 | 0.32 | 0.37 | 13.50 | 1.15 | N2 | 32.15 | 0.31 | 0.40 | 22.50 | 1.29 | N3 | 31.18 | 0.34 | 0.38 | 10.52 | 1.11 | N4 | 32.20 | 0.38 | 0.44 | 13.63 | 1.15 | N5 | 34.80 | 0.30 | 0.35 | 14.28 | 1.16 | N6 | 33.15 | 0.36 | 0.42 | 14.28 | 1.16 | N7 | 30.00 | 0.29 | 0.33 | 12.12 | 1.13 | N8 | 28.55 | 0.30 | 0.35 | 14.28 | 1.16 | N9 | 27.50 | 0.31 | 0.35 | 11.42 | 1.13 | N10 | 31.85 | 0.39 | 0.46 | 15.21 | 1.18 | N11 | 27.90 | 0.34 | 0.40 | 15.00 | 1.17 | N12 | 34.55 | 0.39 | 0.45 | 13.33 | 1.15 | N13 | 34.41 | 0.33 | 0.38 | 13.15 | 1.15 |
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