Research Article

Transthyretin and Amyloid in the Islets of Langerhans in Type-2 Diabetes

Figure 5

In (a) is shown an islet from a type-2 diabetic individual. There is pronounced IAPP amyloid infiltration, weakly labeled with antibodies against TTR. (b) shows a small islet in a nondiabetic individual with familial TTR-amyloidosis. There are heavy deposits of TTR-amyloid outside the islet but no islet amyloid. A  =  amyloid. Immunolabeled with antiserum against TTR.
429274.fig.005a
(a)
429274.fig.005b
(b)