Review Article
Intracellular Signalling by C-Peptide
Table 1
Signalling elements activated by C-peptide according to cell type
studied (for abbreviations see text).
| Cell type studied | | Signalling element | Kidney tubular | Muscle | Fibroblasts | Endothelial | Erythrocytes | Neuroblastoma | CD4 + T Cells | Nerve |
| Na+,K+-ATPase | + | | | | + | | | + | [Ca2+]i | + | | | + | | | | | PKC | + | | + | | | | | | NO release | | + | | + | | | | | ERK | + | + | + | + | | | | | p38 MAPK | | | | + | | | | | JNK | + | | | | | | | | PLC | + | | | | | | | | p90RSK | | + | | | | | | | GSK3 | | + | | | | | | | PI3K | + | + | | + | | + | + | | CREB | | | | + | | | | | NF-κB | + | | + | | | + | | | PPAR | + | | | | | | | |
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