Human Islet Amyloid Polypeptide Transgenic Mice: In Vivo and Ex Vivo Models for the Role of hIAPP in Type 2 Diabetes Mellitus

<table>Comparison of the average labeling density of GLUT-2 mRNA in situ hybridization in
pancreatic islets from nontransgenic (NT) and hIAPP transgenic (hIAPP) mice (<i>P</i> = .02). For both groups 4 mice were analysed, 2 males, and 2 females. The 4
transgenic mice did not have amyloid.</table>

Journal of Diabetes Research

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Figure 3: Human Islet Amyloid Polypeptide Transgenic Mice: In Vivo and Ex Vivo Models for the Role of hIAPP in Type 2 Diabetes Mellitus 