Real-Time Monitoring of Apoptosis by Caspase-3-Like Protease Induced FRET Reduction Triggered by Amyloid Aggregation
Figure 3
Congo red staining and electron
micrographs of amyloid-like fibrils from recproIAPP,
recN+IAPP, recIAPP,
and recIAPP+C.
Congo red
staining viewed in polarised light showing amyloid specific green birefringence
of (a) recproIAPP, (c) recN+IAPP, (e)
recIAPP, and (g)
recIAPP+C.
Scale bars represent 20 m. Electron micrographs of negative contrasted
amyloid-like fibrils of (b) recproIAPP, (d)
recN+IAPP, (f)
recIAPP,
and (h) recIAPP+C. Scale bars represent 100 nm.