Clinical Study

Trp64Arg Polymorphism in Beta3-Adrenergic Receptor Gene Is Associated with Decreased Fat Oxidation Both in Resting and Aerobic Exercise in the Japanese Male

Table 1

The physical characteristics and energy expenditure in subjects with the 3-AR Trp64Arg polymorphism. Data are expressed as means ± SD. .05.

 MaleFemale
 Trp/TrpTrp/Arg Trp/TrpTrp/Arg

Arg/ArgArg/Arg
Number of subjects 29 64.4% 16 35.6% 23 56.0% 18 44.0%
Age (years) 21.6 ±2.3 23.1 ±3.90.16 21.6 ±2.8 22.7 ±5.30.42
Height (cm) 172.7 ±5.1 171.5 ±6.80.55 158.3 ±5.1 159.8 ±6.50.39
Weight (kg) 68.7 ±9.3 68.3 ±15.20.90 56.8 ±7.3 53.7 ±7.50.18
BMI (kg/m2 23.0 ±2.7 23.2 ±5.00.87 22.7 ±3.2 21.0 ±2.50.06
Lean body mass (kg) 52.3 ±4.6 51.1 ±6.50.47 37.4 ±5.3 35.6 ±2.70.21
In the resting state
(kcal/kg/30min)
Energy expenditure0.72 ±0.130.69 ±0.110.47 0.69 ±0.110.70 ±0.140.47
Fat oxidation0.38 ±0.180.23 ±0.160.01 0.38 ±0.180.32 ±0.150.29
Carbohydrate oxidation0.34 ±0.170.46 ±0.120.01 0.31 ±0.180.38 ±0.140.20
During the aerobic exercise
(kcal/kg/30min)
Energy expenditure3.12 ±0.483.07 ±0.44 0.742.24 ±0.332.34 ±0.27 0.33
Fat oxidation1.00 ±0.380.78 ±0.280.050.74 ±0.290.76 ±0.32 0.89
Carbohydrate oxidation2.12 ±0.442.29 ±0.38 0.22 1.50 ±0.411.58 ±0.36 0.48