Rosiglitazone Prevents High Glucose-Induced Vascular Endothelial Growth Factor and Collagen IV Expression in Cultured Mesangial Cells
Figure 6
PKC-β 1 and PKC-ζ response to high glucose and rosiglitazone . Mesangial cells were exposed to 5.6 mM (NG) or 25 mM (HG) for 3 hours or 48 hours pretreated with 10 M rosiglitazone (RSG) for 1 hour. PKC- and PKC- were detected in total cell lysates or membrane fractions with immunoblotting. (a) Representative immunoblots of PKC- and PKC-ζ. (b) Quantitative analysis of the immunoblots (, versus NG without RSG, versus HG without RSG).
