Research Article
High Glucose Increases Metallothionein Expression in Renal Proximal Tubular Epithelial Cells
Table 1
Metabolic data at 1, 2, and 8 weeks after inducing diabetes.
| | | 1 week | 2 week | 8 week |
| Body weight (g) | | | | | Control | | 204 ± 6.3 | 241 ± 10.4 | 380 ± 13.3 | Diabetic | | 198 ± 4.7 | 225 ± 11.5 | 248 ± 16.6* | Kidney weight (mg/g BW) | | | | | Control | | 5.8 ± 0.4 | 5.6 ± 0.8 | 4.5 ± 0.7 | Diabetic | | 5.9 ± 0.6 | 6.1 ± 1.0 | 6.7 ± 0.9* | UAE (μg/day) | | | | | Control | | 110 ± 7.3 | 121 ± 8.1 | 137 ± 14.7 | Diabetic | | 116 ± 5.7 | 125 ± 9.4 | 458 ± 24.5* | HbA1c (%) | | | | | Control | | 3.7 ± 0.4 | 3.8 ± 0.6 | 3.8 ± 0.5 | Diabetic | | 3.8 ± 0.3 | 4.3 ± 0.7 | 7.8 ± 0.9* |
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Data are means ± SEM; * versus the control group. BW: body weight; UAE: urinary albumin excretion; HbA1c: hemoglobin A1c.
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