Table 2: Effect of treatment of streptozotocin-diabetic rats with alogliptin on serum thio barbituric acid reactive substances, triglycerides, free fatty acids, cholesterol and dipeptidyl peptidase-IV activity.

DeterminationControl
(11)
Diabetic
(12)
Diabetic + Alogliptin
(9)

TBARS (μg/mL)0.78 ± 0.071.07 ± 0.06a0.93 ± 0.12
Triglycerides (mg/dL)25 ± 3206 ± 27a225 ± 46a
Free fatty acids (mmol/L)0.11 ± 0.030.56 ± 0.07a0.41 ± 0.11a
Cholesterol (mg/dL)82 ± 13223 ± 38a175 ± 35a
Dipeptidyl peptidase-IV
activity (ng/mL)
24.0 ± 3.035.4 ± 5.118.3 ± 3.4b

Data are presented as the mean ± SEM. aP < 0.05 compared to control; bP < 0.05 compared to diabetic. Parentheses indicate the number of experimental animals.