Impaired Sympathoadrenal Axis Function Contributes to Enhanced Insulin Secretion in Prediabetic Obese Rats

Figure 6

The effect of the α-adrenergic agonist oxymetazoline on glycaemia (a) and insulinaemia (b) during ivGTT in MSG-obese rats. Bars represent mean ± SEM (n = 8–10 animals per group). A Student’s t-test or ANOVA was used where appropriate. *𝑃<0.05 compared to control. The letters over the bars represent a significant difference: a: 𝑃<0.05 versus control; b: 𝑃<0.05 versus control-oxymetazoline; c: 𝑃<0.05 versus MSG; d: 𝑃<0.05 versus MSG xymetazoline.

(a)

(b)