Early Degenerative Effects of Diabetes Mellitus on Pancreas, Liver, and Kidney in Rats: An Immunohistochemical Study
Figure 2
COX-2 reactions. (a) Severe positive immunoreaction in endocrine islets of pancreas in study group (arrows), Bar = 50 μm. (b) No immunoreaction in Langerhans islets of pancreas in control group, Bar = 100 μm. (c) Moderate immunoreaction in hepatocyte in study group (arrows), Bar = 100 μm. (d) A few immunoreactions in liver (arrows) in control group, Bar = 50 μm. (e) Strong immunopositive reaction in nonmacula densa area in kidney (arrows) in study group, Bar = 100 μm. (f) A few immunoreactions in kidney tubul cells in macula densa (arrows) in control group, Bar = 100 μm. ABC-P method with hematoxylin counterstaining was used for all tissues. The right column belongs to study group and left column is belong to control group.
