147965.fig.004a
(a)
147965.fig.004b
(b)
Figure 4: Stereoview of ALR2 docked with gentiopicroside. (a) Gentiopicroside docked into the active site of ALR2 and extended towards hydrophobic pocket.  (b) Gentiopicroside docked into active site of ALR2 and depicts its hydrophobic interactions with Trp-219, Phe-122, and Leu-301 (dotted line).