| Animal species | Animal strains | Dose of STZ (mg/kg body weight) | Time of injection | Solvent | Method of injection | References |
| | ICR | 90–150 | 1 | Citrate buffer, pH 4.5 | i.p | [40, 43, 45, 48] | | | 70 | 3 | Citrate buffer, pH 4.5 | i.p | [58] | | | 130–225 | 1 | Citrate buffer, pH 4.5 | i.p | [42, 44, 46, 47] | Mice | C57BL/6 | 75–100 | 3 | | i.v | [59, 60] | | | 40–65 | 5 | Citrate buffer, pH 4.5 | i.p | [49–54] | | BALB/c | 150 | 1 | Citrate buffer, pH 4.5 | i.p | [61] | | | 50 | 5 | | i.p | [62] |
| | | 60–85 | 1 | Citrate buffer, pH 4.5 | i.p | [60, 63–65] | | Sprague-Dawley | 55–60 | 1 | | i.v | [66, 67] | | | 50 | 6 | Citrate buffer, pH 4.5 | i.v | [68] | Rat | | 50–70 | 1 | Citrate buffer, pH 4.5 or Normal saline | i.p | [69–74] | | Wistar | 40 | 5 | Citrate buffer, pH 4.5 | i.p | [75] | | | 50–65 | 1 | Citrate buffer, pH 4.5 | i.v | [55–57] |
| Dog | Beagle | 30–50 | 1 | | i.v | [76–78] |
| Velvet Monkey | Chlorocebus aethiops | 45–55 | 1 | Normal saline | i.v | [79, 80] |
| Cynomolgus Monkey | Macaca fascicularis | 68–150 | 1 | Citrate buffer, pH 4.5 | i.v | [41, 81, 82] |
| | Yucatan | 125 | 1 | | i.v | [83] | | Yorkshire | 50 | 1 | Citrate buffer, pH 4.5 | i.v | [84] | Pig | Landrace | 125 | 1 | | i.v | [85] | | Dutch Landrace X Yorkshire X Finnish Landrace | 120 | 1 | | i.v | [86] | | domestic | 90 | 1 | Normal saline | i.v | [87] |
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