Amelioration of Glucolipotoxicity-Induced Endoplasmic Reticulum Stress by a “Chemical Chaperone” in Human THP-1 Monocytes

Figure 1

(a) Representative confocal microscopy images of Intracellular ROS generation in cells treated under various conditions. (b) Mean (±SEM) fluorescence intensities of ROS under different experimental maneuvers, namely, control, glucolipotoxicity (GLT), glucolipotoxicity + 4-phenyl butyric acid (GLT + PBA), tunicamycin (Tun), tunicamycin + 4-phenyl butyric acid (Tun + PBA), 4-phenyl butyric acid (PBA). *𝑃<0.05 compared to control, ^#𝑃<0.05 compared to GLT, **𝑃<0.05 compared to tunicamycin.

(a)

(b)