Research Article

Comparison of Oxidant/Antioxidant, Detoxification Systems in Various Tissue Homogenates and Mitochondria of Rats with Diabetes Induced by Streptozocin

Table 2

Evaluation of parameters measured in the mitochondrial fraction of both group by tissue types.

MeasurementLung X ± SLiver X ± SKidney X ± SHeart X ± S

MDA (nmol/L)
Control4,23 ± 0,59#6,04 ± 0,12# 2,54 ± 0,67#1,21 ± 0,29#
Diabetic2,90 ± 2,006,21 ± 4,634,43 ± 3,811,61 ± 0,99

TAS (mmol trolox Equiv/L)
Control0,79 ± 0,860,69 ± 0,551,46 ± 0,320,83 ± 0,59
Diabetic0,51 ± 0,102,11 ± 1,651,28 ± 0,200,42 ± 0,15

TOS (μmol H2O2 Equiv/L)
Control8,83 ± 11,79 7,82 ± 9,312,27 ± 0,791,57 ± 1,28
Diabetic1,87 ± 0,3510,00 ± 7,092,19 ± 0,760,85 ± 0,33

OSİ (%)
Control8,66 ± 5,0316,10 ± 21,67§1,52 ± 0,28§1,82 ± 0,32§
Diabetic3,84 ± 1,445,59 ± 2,15*1,68 ± 0,22*2,20 ± 1,0

PON (U/L)
Control6,00 ± 2,0011,66 ± 12,507,33 ± 2,088,00 ± 1,00
Diabetic7,33 ± 0,5710,66 ± 5,857,33 ± 1,529,66 ± 2,88

Arylesterase (U/L)
Control5006,6 ± 742,04330,6 ± 951,44636,3 ± 210,73996,3 ± 183,9
Diabetic3583,6 ± 1487,64460,6 ± 449,5 4348,0 ± 165,33996,6 ± 136,0

GST (U/mgPrt)
Control0,0027 ± 0,0010,0307 ± 0,0160,0063 ± 0,0040,0077 ± 0,005
Diabetic0,0023 ± 0,00070,0272 ± 0,0030,0038 ± 0,0010,0087 ± 0,004

Catalase (U/mgPrt)
Control0,0126 ± 0,004ξ0,0655 ± 0,0320,1005 ± 0,047ξ0,0254 ± 0,02
Diabetic0,0086 ± 0,003§0,0575 ± 0,024§0,0429 ± 0,00940,0266 ± 0,009

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