Research Article
Hepatic Mitochondrial Alterations and Increased Oxidative Stress in Nutritional Diabetes-Prone Psammomys obesus Model
Table 2
Effect of dietary treatment on respiratory control ratios (RCR) of liver mitochondria from both Psammomys groups. *P < 0.05 versus control group.
| | | Oxygen consumption rate (natoms O/min/mg protein) | | | Glutamate/Malate (GM) | Succinate/Malate (SM) + rotenone | | State 3 | State 4 | RCR | State 3 | State 4 | RCR |
| Control | 138.8 ± 9.9 | 14.8 ± 0.6 | 9.4 ± 0.9 | 143.1 ± 5.3 | 39.3 ± 3.0 | 3.7 ± 0.3 | Diabetic | 96.1 ± 7.3* | 14.5 ± 0.6 | 6.6 ± 0.2* | 133.0 ± 12.3 | 35.4 ± 3.5 | 3.8 ± 0.2 |
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