Antioxidant Sol-Gel Improves Cutaneous Wound Healing in Streptozotocin-Induced Diabetic Rats
Figure 8
Effect of antioxidant sol-gel on apoptosis production of the healing skin in diabetic rats at 7th day. Apoptosis analyzed by TUNEL stain (brown color in the nucleus) was shown in the saline control (a), Pluronic F127 sol (b), saline plus vitamin C (c), and Pluronic F127 plus vitamin C (d). The data were expressed as the number of apoptosis (high power field) in each section (400x) is displayed in (e). The percentage of apoptosis appearance in the wounds is demonstrated in an order of FC > SC > F > S 14 days after wounding (e). Data are expressed as mean ± SEM. *P < 0.05 when compared to saline group. S: saline control; F: Pluronic F127; SC: saline plus vitamin C; FC: Pluronic F127 plus vitamin C. Original magnifications taken at ×200.
