A PEDF-Derived Peptide Inhibits Retinal Neovascularization and Blocks Mobilization of Bone Marrow-Derived Endothelial Progenitor Cells

Figure 6

The number of circulating endothelial cells and EPCs increases in OIR mice at P16. Tie2-GFP⁺ cells in both the bone marrow (BM) and peripheral blood (PB) from Tie2-GFP mice were quantified by FACS at p12, p16 and p20 under normoxic rearing conditions (grey), or in the OIR model (black). Graphs represent the percent of Tie2-GFP⁺ cells based on 100% being set to the average number of Tie2-GFP⁺ cells from normoxic mice.

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