Table 1: Selected clinical trials of corticosteroids in treatment of diabetic macular edema.

Agent (no. patients)Main outcomesReference

Intravitreal triamcinolone (693)Less favorable outcomes versus photocoagulation at 24 and 36 months[22, 23]
Peribulbar triamcinolone (109)Less favorable outcomes versus intravitreal triamcinolone at 34 weeks[28]
Fluocinolone acetonide implant (Retisert) (197)Effective treatment of DME at 36 months, but high risks of cataract and glaucoma[32]
Fluocinolone acetonide implant (Iluvien) (956)Generally favorable results at 24 months[34]
Dexamethasone drug delivery system (Ozurdex) (171)Generally favorable results at 90 days[36]