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Study no. [reference] | Year author | Country | Name of study | Study design | Number of cases/ Follow-up duration | Estimated risk |
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1 [17] | 1991 Adami et al. | Sweden | Cancer risk in patients with diabetes mellitus | Population-based cohort study | 51,008 patients. Cohort established by identifying diabetic patients during 1965–1983. Complete followup through 1984 | Women: RR = 1 (95% CI: 0.6–1.8) Men: RR = 1.3 (95% CI: 0.5–2.8) |
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2 [18] | 1997 Wideroff et al. | Denmark | Cancer incidence in a population-based cohort of patients hospitalized with diabetes mellitus in Denmark | Prospective cohort study | 109,581 diabetics. Cohort established by identifying diabetic patients during 1977–1989. Cohort exit date: date of death or 1993 | Women: SIR = 1.3 (95% CI: 0.6–2.3) Men: SIR = 1.2 (95% CI: 0.7–1.8) |
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3 [19] | 2006 Inoue et al. | Japan | The Japan Public Health Center-based Prospective Study | Prospective cohort study | 46,548 women, 51,223 men Followed from 1990 through 2003 | Women: HR = 1.11 (95% CI: 0.35–3.5) Men: NA |
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4 [20] | 2007 Kuriki et al. | Japan | Hospital based Epidemiologic Research Program at Aichi Cancer Center, Japan | Case-control study | 11,672 incident cancer cases (5341 men, 6331 women) 47,768 cancer-free controls (14,199 men, 33,569 women) | Women: OR = 0.67 (95% CI: 0.21–2.10) Men: OR = 1.07 (95% CI: 0.33–3.48) |
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5 [13] | 2010 Meinhold et al. | USA | The US Radiologic Technologists Study | Prospective cohort study | 69,506 women, 21,207 men Followed from 1983 through 2006 | Women: HR = 1.37 (95% CI: 0.49–3.77) Men: NA |
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6 [21] | 2010 Chodick et al. | Israel | Diabetes and risk of incident cancer: a large population-based cohort study in Israel | Retrospective cohort study | 16,721 DM, 83,874 non-DM Mean follow-up time: 8 years | Women: HR = 1.61 (95% CI: 0.96–2.69) Men: HR = 0.72 (95% CI: 0.25–2.04) |
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7 [22] | 2011 Aschebrook-Kilfoy et al. | USA | The NIH-AARP Diet and Health Study | Prospective cohort study | 200,556 women, 295,992 men Mean follow-up time: 10 years | Women: HR = 1.54 (95% CI: 1.08–2.20) Men: HR = 1.11 (95% CI: 0.74–1.66) |
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8 [23] | 2012 Kitahara et al. | USA | Physical activity, diabetes, and thyroid cancer risk: a pooled analysis of five prospective studies | Pooled analysis of five prospective studies, including NIHAARP Diet and Health Study (NIH-AARP), Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO), Breast Cancer Detection and Demonstration Project (BCDDP), Agricultural Health Study (AHS), and US Radiologic Technologists Study (USRT) | 312,149 women, 362,342 men Median follow-up time: 10.5 years | Women: HR = 1.19 (95% CI: 0.84–1.69) Men: HR = 0.96 (95% CI: 0.65–1.42) |
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