Blockade of Renin Angiotensin System Increased Resistance to STZ-Induced Diabetes in Rats with Long-Term High-Fat Diet

Table 3

Quantitive analysis of RT-PCR and immunohistochemistry results (𝑥±𝑠).

Group	𝑛	ARC	ILRC	IRC	ICD	NRC	CRC	AC
NC	5	0.73±0.20	0.57±0.13	−4.14±0.14	2.51±0.26	−5.02±0.19	−5.18±0.11	0.21±0.05
HF	5	1.61±0.19^∗	1.57±0.22^∗	−5.20±0.09^∗	2.37±0.08	−3.99±0.33^∗	−4.19±0.12^∗	0.72±0.10^∗
HF+S	5	1.95±0.11^∗#	1.93±0.17^∗#	−5.42±0.07^∗#	1.45±0.14^∗#	−3.40±0.14^∗#	−3.84±0.11^∗#	0.98±0.04^∗#
HF+T+S	5	1.72±0.14^∗★	1.67±0.11^∗★	−5.33± 0.05^∗▴★	1.78±0.12^∗#∇	−3.62±0.12^∗▴★	4.02±0.07^∗▴★	0.84±0.06^∗▴∇

ARC: AT1R mRNA relative content; ILRC: IL-1𝛽 mRNA relative content; IRC: insulin raltive concentration; ICD: insulin positive cell density; NRC: NF-𝜅B relative concentration; CRC: caspase-3 relative concentration; AC: apoptosis cells of unit islet area.
NC: normal control group; HF: high-fat diet group; HF+S: high-fat diet plus STZ intraperitoneal injection group; HF+T+S: high-fat diet plus telmisartan intervention and STZ intraperitoneal injection group.
^●P < 0.05; ^∗𝑃<0.01 as compared with NC group; ^▲P < 0.05, ^#<0.01 as compared with HF group; ^★<0.05, ^∇<0.01 as compared with HF+S group.