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Experimental Diabetes Research
Volume 2012 (2012), Article ID 672013, 10 pages
Combined Transfection of the Three Transcriptional Factors, PDX-1, NeuroD1, and MafA, Causes Differentiation of Bone Marrow Mesenchymal Stem Cells into Insulin-Producing Cells
1Department of General Surgery, Affiliated Hospital of Nantong University, Nantong 226001, China
2Department of Surgical Comprehensive Laboratory, Affiliated Hospital of Nantong University, Nantong 226001, China
Received 24 December 2011; Revised 1 April 2012; Accepted 30 April 2012
Academic Editor: Joseph R. Landolph Jr.
Copyright © 2012 Guo Qing-Song et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citations to this Article [10 citations]
The following is the list of published articles that have cited the current article.
- Saman Rahmati, Najva Alijani, and Mehdi Kadivar, “In vitro generation of glucose-responsive insulin producing cells using lentiviral based pdx-1 gene transduction of mouse (C57BL/6) mesenchymal stem cells,” Biochemical and Biophysical Research Communications, vol. 437, no. 3, pp. 413–419, 2013.
- Hiroshi Takemitsu, Dongwei Zhao, Shingo Ishikawa, Masaki Michishita, Toshiro Arai, and Ichiro Yamamoto, “Mechanism of insulin production in canine bone marrow derived mesenchymal stem cells,” General and Comparative Endocrinology, vol. 189, pp. 1–6, 2013.
- Ting-Ting Zhou, Chao Wei, Xiao-Dong Chen, Hai Li, and Zheng Wang, “Primary culture of umbilical cord-derived mesenchymal stem cells in serum free medium,” Chinese Journal of Tissue Engineering Research, vol. 17, no. 27, pp. 4980–4987, 2013.
- Devang M. Patel, Jainy Shah, and Anand S. Srivastava, “Therapeutic Potential of Mesenchymal Stem Cells in Regenerative Medicine,” Stem Cells International, vol. 2013, pp. 1–15, 2013.
- Ashwini Ketkar-Atre, Tom Struys, Stefaan J. Soenen, Ivo Lambrichts, Catherine M. Verfaillie, Marcel De Cuyper, and Uwe Himmelreich, “Variability in contrast agent uptake by different but similar stem cell types,” International Journal of Nanomedicine, vol. 8, pp. 4577–4591, 2013.
- Phuc Van Pham, Phuoc Thi-My Nguyen, Anh Thai-Quynh Nguyen, Vuong Minh Pham, Anh Nguyen-Tu Bui, Loan Thi-Tung Dang, Khue Gia Nguyen, and Ngoc Kim Phan, “Improved differentiation of umbilical cord blood-derived mesenchymal stem cells into insulin-producing cells by PDX-1 mRNA transfection,” Differentiation, 2014.
- Weina Gao, Yuchang Fu, Cong Yu, Shunke Wang, Yuchao Zhang, Chen Zong, Tongfu Xu, Yong Liu, Xia Li, and Xiangdong Wang, “Elevation of NR4A3 Expression and Its Possible Role in Modulating Insulin Expression in the Pancreatic Beta Cell,” Plos One, vol. 9, no. 3, 2014.
- Adam Nowakowski, Piotr Walczak, Miroslaw Janowski, and Barbara Lukomska, “Genetic Engineering of Mesenchymal Stem Cells for Regenerative Medicine,” Stem Cells and Development, pp. 150826083522001, 2015.
- Marina Lizio, Yuri Ishizu, Masayoshi Itoh, Timo Lassmann, Akira Hasegawa, Atsutaka Kubosaki, Jessica Severin, Hideya Kawaji, Yukio Nakamura, Harukazu Suzuki, Yoshihide Hayashizaki, Piero Carninci, and Alistair R. R. Forrest, “Mapping Mammalian Cell-type-specific Transcriptional Regulatory Networks Using KD-CAGE and ChIP-seq Data in the TC-YIK Cell Line,” Frontiers in Genetics, vol. 6, 2015.
- Zahra Mehrfarjam, Fariba Esmaeili, Leila Shabani, and Esmaeil Ebrahimie, “Induction of pancreatic β cell gene expression in mesenchymal stem cells,” Cell Biology International, vol. 40, no. 5, pp. 486–500, 2016.