Effects of Glucagon-Like Peptide-1 Receptor Agonists on Body Weight: A Meta-Analysis

Table 2

Weighted mean differences in 6- and 12-month BMI between GLP-1 receptor agonists and different active comparators.

	Number of trials	6-month BMI	𝑃	12-month BMI	𝑃
Overall	6	−1.2 [−1.5; −0.8]	<0.001	−1.9 [−3.0; −0.8]	<0.001
DPP-4 inhibitors	1	−1.6 [−2.6; −0.8]	<0.001	−1.7 [−2.7; −0.7]	0.001
Sulphonylureas	3	−1.4 [−2.4; −0.7]	0.001	−2.3 [−4.2; −0.5]	0.012
Insulin	2	−0.7 [−1.4; 0.0]	0.048	−1.5 [−2.1; −0.8]	<0.001