Aspects of Inflammation and Oxidative Stress in Pediatric Obesity and Type 1 Diabetes: An Overview of Ten Years of Studies
Figure 1
Plasma interleukin-6 (IL-6) in 47 children with type 1 diabetes before, at the end of, and 30 min after a standardized 30 minute intermittent exercise challenge (a) and exercise-induced IL-6 increments (b). While all children exercised in euglycemic conditions (and had been euglycemic for at least the two hours preceding exercise), they differed in average glycemic control during the previous three days and were therefore subdivided in four groups (11-12 subjects each) with increasing mean prior 3-day glycemia. Children in the group with the lowest mean glycemia (<8 mM, only slightly greater than comparable healthy controls) displayed the lowest IL-6 values at all time points; with greater mean prior glycemia, IL-6 values became progressively higher. Data are group means ± SE. * <8.0 mM group I.
