Cellular Dysfunction in Diabetes as Maladaptive Response to Mitochondrial Oxidative Stress

Table 3

Effects of experimental diabetes in levels of protein carbonyls.

Tissue	Model	Effect	Reference
Mouse
Aorta	BKS.cg-m +/+ Lepr db/J mice versus wild type	↑	[9]
Hippocampus and cerebral cortex	Streptozotocin	↑	[10]
Kidney	Type 2 diabetic db/db versus normoglycemic wild type mouse	↑	[11]
Lenses	Streptozotocin	↑	[12]
Rat
Aorta	Goto-Kakizaki rats	↑	[13]
Bone	Goto-Kakizaki rats	↑	[14]
Brain	Galactose-induced hyperglycemia	↑	[15]
Brain	Goto-Kakizaki rats	↑	[16]
Brain	Streptozotocin	=	[17]
Heart	Streptozotocin	↑	[18]
Heart	Streptozotocin	↑	[19]
Heart	Streptozotocin	↑	[20]
Heart	Streptozotocin	↑	[21]
Heart	Streptozotocin	↑	[17]
Hemoglobin	Streptozotocin	↑	[22]
Intestinal tissue	Streptozotocin	↑	[23]
Kidney	Streptozotocin	↑	[24]
Kidney	Streptozotocin	↑	[18]
Kidney	Zucker obese hyperglycemic rats (ZDFn Gm-fa/fa)	↑	[25]
Kidney	Streptozotocin	↑	[26]
Kidney	Streptozotocin	↑	[17]
Lens proteins	Streptozotocin	↑	[27]
Liver	Streptozotocin	↓	[24]
Liver	Pregnant diabetic rats versus control rats	=	[28]
Liver	Galactose-induced hyperglycemia	↑	[15]
Liver	Streptozotocin	↑	[18]
Liver	Streptozotocin	↑	[29]
Liver	Streptozotocin	↑	[23]
Liver	Streptozotocin	↑	[30]
Liver	Streptozotocin	↑	[17]
Lung	Streptozotocin	↑	[31]
Pancreas	Streptozotocin	↑	[18]
Pancreas	Alloxan	↑	[32]
Pancreas	Streptozotocin	↑	[17]
Pancreas	Streptozotocin	↑	[33]
Plasma proteins	Streptozotocin	↑	[34]
Plasma proteins	Streptozotocin	↑	[35]
Plasma proteins	Streptozotocin	↑	[36]
Red blood cells	Streptozotocin	↑	[18]
Retinal Müller cells	Streptozotocin	↑	[37]
Skeletal muscle	Glupreclamp infusion versus control	↑	[38]
Skeletal muscle	Otsuka Long Evans Tokushima Fatty (OLETF) rats versus LETO rats	↑	[39]
Skeletal muscle (Soleus muscles)	Goto-Kakizaki rats	↑	[13]
Skeletal muscle (Plantaris muscle)	Obese Zucker rats versus lean Zucker rats	↑	[40]
Skeletal muscle	Streptozotocin	↑	[41]
Testis and epididymal sperm	Streptozotocin	↑	[42]
Vascular smooth muscle cells	Glucose incubation	↑	[43]
Rabbit
Heart	Alloxan	↑	[44]
Lens proteins and cells	In vitro incubation	↑	[45]