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Experimental Diabetes Research
Volume 2012 (2012), Article ID 789174, 12 pages
Insulin Resistance and Cancer Risk: An Overview of the Pathogenetic Mechanisms
1Department of Health Sciences, Magna Græcia University of Catanzaro, Viale Europa (Località Germaneto), 88100 Catanzaro, Italy
2Clinical Pathology, Magna Græcia University of Catanzaro, Viale Europa (Località Germaneto), 88100 Catanzaro, Italy
3Endocrinology, Magna Græcia University of Catanzaro, Viale Europa (Località Germaneto), 88100 Catanzaro, Italy
Received 29 January 2012; Accepted 10 April 2012
Academic Editor: Chien-Jen Chen
Copyright © 2012 Biagio Arcidiacono et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citations to this Article [44 citations]
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- K B Greer, A Kresak, B Bednarchik, D Dawson, L Li, A Chak, and J Willis, “Insulin/Insulin-Like Growth Factor-1 Pathway in Barrett’s Carcinogenesis,” Clinical and Translational Gastroenterology, vol. 4, no. 3, pp. e31, 2013.
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- E.M. Strage, M.S. Lewitt, J.M. Hanson, U. Olsson, F. Norrvik, I. Lilliehöök, B.S. Holst, and T. Fall, “Relationship among Insulin Resistance, Growth Hormone, and Insulin-Like Growth Factor I Concentrations in Diestrous Swedish Elkhounds,” Journal of Veterinary Internal Medicine, 2014.
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