Haplotypes in the CRP Gene Associated with Increased BMI and Levels of CRP in Subjects with Type 2 Diabetes or Obesity from Southwestern Mexico

Table 2

Clinical and demographic characteristics of patients in the study groups.

Characteristics	Healthy	T2D without obesity	Obese	T2D with obesity	P value
	𝑛=130	𝑛=93	𝑛=106	𝑛=73
Age (years)	40 (35–47)	56 (46–67)	43 (38–49)	48 (43–59)	<0.001^a
Gender, n (%)
Male	33 (25.4)	30 (32.3)	23 (21.7)	21 (28.8)	0.376^b
Female	97 (74.6)	63 (67.7)	83 (78.3)	52 (71.2)
Body mass index (kg/m^2)	23.6 (22.2–24.6)	24.0 (22.4–24.7)	33.1 (30.8–35.3)	32.0 (30.3–34.3)	<0.001^a
Waist (cm)	82 (76–87)	86 (82–92)	103 (97–108)	103 (98–108)	<0.001^a
Abdominal obesity, n (%)	14 (10.8)	18 (19.4)	97 (91.5)	66 (90.4)	<0.001^b
Systolic blood pressure (mmHg)	107 (95–115)	118 (110–129)	109 (101–123)	112 (103–120)	<0.001^a
Diastolic blood pressure (mmHg)	69 (63–76)	71 (66–79)	72 (67–79)	73 (67–77)	0.006^a
Glucose (mg/dL)	84 (77–89)	174 (120–243)	89 (84–96)	151 (120–222)	<0.001^a
Cholesterol (mg/dL)	197 (167–220)	185 (165–206)	185 (156–218)	184 (161–215)	0.320^a
Triglycerides (mg/dL)	141 (99–187)	181 (126–250)	148 (107–187)	191 (142–249)	<0.001^a
Leukocytes (10^3/μL)	5.8 (5.1–6.2)	6.7 (5.7–6.9)	6.6 (5.7–7.5)	6.4 (5.7–7.0)	<0.001^a
hsCRP (mg/L)*	1.2 (0.17)	1.7 (0.33)	3.6 (0.40)	4.4 (0.45)	<0.001^a
<1	58 (44.6)	27 (29.0)	11 (10.4)	5 (6.8)	<0.001^b
1–3	44 (33.9)	36 (38.7)	25 (23.6)	14 (19.2)
>3	28 (21.5)	30 (32.3)	70 (66.0)	54 (74.0)
CHD risk score	−0.5 (−6, 3)	9 (5, 12)	1 (−5, 4)	6 (4, 9)	<0.001^a

The data indicate median (p25–p75), n (%) *geometric mean (standard error).
^aKruskall-Wallis’s test; ^b𝜒² test.
hsCRP: C-reactive protein high sensitivity. CHD: coronary heart disease.