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Journal of Diabetes Research
Volume 2013 (2013), Article ID 103731, 9 pages
http://dx.doi.org/10.1155/2013/103731
Research Article

A Novel Rat Model of Type 2 Diabetes: The Zucker Fatty Diabetes Mellitus ZFDM Rat

1Division of Cellular and Molecular Medicine, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan
2Division of Molecular and Metabolic Medicine, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan
3Hoshino Laboratory Animals, Inc., Ibaraki 306-0606, Japan
4Animal Research Center, Tokyo Medical University, Tokyo 160-8402, Japan
5Japan SLC, Inc., Hamamatsu 431-1103, Japan
6Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan
7The Integrated Center for Mass Spectrometry, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan

Received 22 November 2012; Accepted 4 January 2013

Academic Editor: Takahisa Yamada

Copyright © 2013 Norihide Yokoi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplemental Figure 1: Comparison of phenotypes between fa/fa rats in the ZFDM and ZF strains. (a) body weight and (b) non-fasting blood glucose level of ZFDM (n=13) and ZF (n=9) male rats. Welch’s t test was used for comparisons between ZFDM and ZF strains.

  1. Supplementary Figure