The Role of Adrenomedullin in the Renal NADPH Oxidase and (Pro)renin in Diabetic Mice

Figure 4

Western blotting of prorenin in the kidneys. The bands for prorenin are demonstrated at the molecular weight of 45 kD, and the densitometry of the bands is shown below (𝑛=4). Wild-C: wild-control mice, Wild-DM: wild mice with streptozotocin-induced diabetes, AMKO-C: adrenomedullin gene knockout (AMKO) mice without treatment (control), and AMKO-DM: AMKO mice with streptozotocin-induced diabetes. ^∗𝑃<0.05 versus Wild-C, ⁺𝑃<0.01 versus AMKO-C, and ^#𝑃<0.05 versus Wild-DM.