Outcome of Acute Renal Injury in Diabetic Mice with Experimental Endotoxemia: Role of Hypoxia-Inducible Factor-1α
Figure 7
AGE and LPS induce HIF-1α upregulation and cooperate to over-increase HIF-1α expression. (a) AGE induces HIF-1α upregulation. (b) LPS induces HIF-1α upregulation and synergizes with AGE to over-increase HIF-1α expression. Equal protein loading was confirmed by probing with an anti-β-actin antibody. Normalized density ratio of HIF-1α over β-actin is indicated for each band.