Research Article

In Vivo Efficacy of HD0471953: A Novel GPR119 Agonist for the Treatment of Type 2 Diabetes Mellitus

Figure 2

Effect of a single treatment of HD0471953 on oral glucose tolerance under normal and fasting conditions in normal mice. (a) The effect on plasma glucose levels in normal mice during an OGTT. (b) The area under the plasma glucose concentration time curve for 2 h (AUC0-2 h) in an OGTT. (c) The effect on plasma GLP-1 levels in normal mice during an OGTT. (d) The effect on plasma insulin levels in normal mice during an OGTT. Data are presented as the mean ± SE for each group ( ). versus vehicle, versus vehicle.
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