Research Article

Ampicillin-Improved Glucose Tolerance in Diet-Induced Obese C57BL/6NTac Mice Is Age Dependent

Figure 6

Significant differences in ileum mRNA expression as revealed by qPCR in diet-induced obese C57BL/6 mice treated or not treated with Ampicillin from birth and until five weeks of age (1A; Ampicillin 5w+ 16w−/DIO+), from 12 to 16 weeks of age (2A; Ampicillin 5w− 16w+/DIO+), at both points in time (1B; Ampicillin 5w+ 16w+/DIO+), or not at all (2B; Ampicillin 5w− 16w−/DIO+), as well as low-fat fed control mice (3; Ampicillin 5w− 16w−/DIO−). Interleukin 18 (IL 18), Lactase (Lct), serum amyloid A (Saa2), tumor necrosis factor (Tnf), Tumor necrosis factor ligand superfamily 15 (Tnfsf15). (a): SAA ( ), IL-18 ( ). (b): Lct ( ), Tnf ( ), SAA ( ), **Tnfsf15 ( ).
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(a)
319321.fig.006b
(b)