IL-10 Induction from Implants Delivering Pancreatic Islets and Hyaluronan
Figure 3
Kinetics of release of HA from alginate in vitro. Alginate spheres (2% alginate/10 L volume/2.2 mm diameter) incorporating 2.5 g of FITC-labeled 120 kDa HA (closed circles) or FITC-labeled Da HA (open circles) were cultured at 37°C in DPBS Ca/Mg, and the media collected at specific time points for measurement of released HA. Essentially all (98%) of the 120 kDa HA was released over 14 days, whereas less than 5% of the Da HA was released during this time period. Error bars = standard deviations (error bars for the Da group are within the diameter of the open circles). spheres for each group.
